Recently, the sodium (Na)/potassium (K) ratio was reported to be associated with blood pressure (BP). A Na/K ratio self-monitoring device using spot urine was established recently. Here, we assessed whether the urinary Na/K ratio change measured using the Na/K device was associated with BP change in a health checkup setting. We targeted 12,890 participants who attended the health checkup in Tome City, Miyagi between 2017 and 2018. Tome City introduced urinary Na/K ratio measurements during health checkups since 2017. For each year, we compared the baseline characteristics according to the urinary Na/K ratio and BP level. We assessed the relationship between change in urinary Na/K ratio and BP change using multiple regression analyses adjusted for age, sex, and change caribbeancupid ücretsiz in body mass index (BMI) and alcohol intake. The average urinary Na/K ratio was significantly lower in 2018 than in 2017 (5.4 ± 3.0 to 4.9 ± 2.2, P < 0.01). The systolic BP of the participants in 2018 (130.9 ± 17.4 mmHg) was lower than that in 2017 (132.1 ± 17.9 mmHg). Moreover, the change in systolic BP and diastolic BP was positively associated with the change in urinary Na/K ratio. In conclusion, the association of the change in urinary Na/K ratio with hypertension and changes in systolic and diastolic BP can be explained by a change in alcohol intake, BMI, and urinary Na/K ratio. Therefore, measuring the urinary Na/K ratio in community settings is a potential population approach for counteracting hypertension.
Addition
Has just, it actually was reported that this new sodium (Na)/potassium (K) proportion was regarding the hypertension (BP) inside the a combination-sectional analysis [1,dos,3,4]. That is expected while the high Na and you will K intake is actually understood to get related to high and low BP, respectively [5,six,7]. Concurrently, studies have become conducted to the source philosophy and issues leading to this new Na/K proportion before year [8, 9].
Sodium/potassium proportion transform was on the blood circulation pressure changes: likelihood of population method for sodium/potassium proportion reduction in health checkup
Into the a residential area means, it is difficult for people to assess the genuine Na consumption due to the fact Na intake is typically assessed from the twenty-four-h pee collection. Even in the event several equations to have estimating Na intake or K intake playing with everyday destination pee had been has just built, this type of equations are not perfect adequate to render views on some one [10,eleven,12]. Also, once the formula need calculating Na, K, and you can creatinine accounts within the a lab, it will take weeks to obtain the outcomes for people. Although players realize that sodium reduction is perfect for minimizing BP, he has got not a way away from assessing its Na level.
Recently, good Na/K proportion notice-keeping track of product having fun with location pee are established . Although it didn’t assess the real Na intake top, it does offer viewpoints regarding the urinary Na/K equilibrium within minutes. Additionally, a keen interventional or observational research with this particular display screen ideal this could be a good equipment to help you estimate the newest urinary Na/K ratio [thirteen, 14].
Therefore, while we have no means to fix assess the Na/K ratio inside the health checkup settings, i considered that examining the brand new urinary Na/K proportion for the a health checkup site could have the potential to include views toward standard population regarding their Na/K proportion and can even have an effect on perception changes, improvement in action, Na/K ratio reduction, and you can BP avoidance. Within this investigation, we examined perhaps the urinary Na/K ratio change mentioned towards Na/K ratio dimension product was with the BP alter independent out of confounding activities for example body mass index (BMI) transform and change for the alcoholic drinks intake and you can opposed the brand new BP top and you can urinary Na/K ratio at neighborhood height.